Zena Max – AMD Human Factor V Leiden Real Time PCR Detection Kit
|Product name||Technology||Package||Catalogue No|
|AMD Human Factor V (Leiden mutation) kit||One step Real time PCR||100 reactions||KD177648-100|
Factor V Leiden (FVL), an inherited thrombophilia, is the most common genetic risk factor for venous thrombosis. The FVL mutation is a G>A single nucleotide polymorphism (SNP) in the Factor V gene resulting in an arginine to glutamine (R506Q) amino acid change. This causes the protein to resist degradation, which disrupts the natural anticoagulant system.
This kit is an in vitro real-time PCR test for the qualitative detection of the Factor V Leiden G1691A mutation in human whole blood samples. It is based on allele specific PCR with hydrolysis probe detection and is a highly sensitive qPCR kit.
The Zena Max Human Factor V Leiden qPCR kit is sensitive down 200 copies per 25uL reaction under our validation methods and devices. The AMD Human Factor V Leiden qPCR kit is up to 100% specific for the Human Factor V Leiden G1691A mutation under our validation methods and devices.