Methylenetetrahydrofolate reductase MTHFR 677
Homozygosity for the methylenetetrahydrofolate reductase (MTHFR) C677T mutation has been associated with elevated plasma homocysteine concentration. This is a major risk factor for venous thrombosis and renal vein thrombosis (RVT), the formation of a clot in the vein that transports blood from the kidneys, leading to a decrease in the drainage of one or both kidneys and the migration of the clot to other parts of the body.
The assay is an in vitro real-time PCR test for the qualitative detection of the MTHFR C677T point mutation using human whole blood samples in EDTA. It is based on allele specific PCR with hydrolysis probe detection and is a highly sensitive qPCR kit.
All AMD kits are manufactured under high quality standard methods and unique precision, comparable with other leading commercial MTHFR diagnostic kits.
The Zena Max MTHFR C677T qPCR kit is very sensitive under our validation methods and devices.
The Zena Max MTHFR C677T qPCR kit is up to 100% specific for the MTHFR C677T mutation under our validation methods and devices.
|Product name||Technology||Package||Catalogue No|
|AMD Methylenetetrahydrofolate reductase (MTHFR) C677T kit||Real-time PCR||100 reactions||KD6466372-100|