Macrolide, Lincosamide and Streptogramin antibiotics are distinct chemicals but their mechanism of action are all similar by inhibiting protein synthesis. They are effective against a broad range of gram positive and gram negative bacteria, however resistance against Macrolide, Lincosamide and Streptogramin antibiotics can be caused by the methylation of 23S rRNA. The expression of methylases, which add methyl groups to 23S rRNA, prevent antibiotics from binding effectively. The AMD Macrolide, Lincosamide and Streptogramin resistance kit quantitatively detects 3 of the main genes responsible for reduced binding.
The range of assays described below are in vitro PCR reaction assays for the quantitative determination of msrA, ermC and ermA genes within antibiotic resistant bacterial cells. Gene expression can be measured using samples such as whole blood based on Taqman detection method for msrA, ermC and ermA with a highly sensitive one step qPCR kit.
Quality: All AMD kits are manufactured under high-quality standardization methods with unique precision and sensitive technology when compared to the most of the famous and approved diagnostic commercial Macrolide, Lincosamide and Streptogramin qPCR assays.
Specificity: AMD Macrolide, Lincosamide and Streptogramin Resistance Kit shows up to 100% specificity for msrA, ermC and ermA genes under our validation methods and devices.
When placing an order, please quote the reference number:
|Product name||Technology||Target Genes||Package||Cat No|
|Macrolide, Lincosamide and Streptogramin Resistance Kit||One step Real time PCR||msrA, ermC and ermA||100 reactions||KD347524-100|